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Abstract
Obesity is a global and constantly growing health problem of modern humanity. Except in economically developed
countries, it is increasingly common in developing countries as well.
It is significantly more common in adults than in children, as well as in women than in men.
It is estimated that around 10% of school-aged children in the world are over nourished, of which a quarter are obese.
Numerous studies show that in parallel with the expansion of obesity, the frequency of its severity also increases, as well as
the number and severity of the complications it carries. In addition, it has been proven that the majority of obese children
and adolescents remain permanently obese, and that pre-adult obesity, apart from its immediate consequences,
significantly contributes to cardiovascular and other problems in adulthood. Therefore, optimal nutrition during childhood
is an extremely important factor, not only for health and adequate growth and development but also for the prevention of
obesity and its consequences in the later stages of life.
Keywords: obesity, children and adolescents, prevention
Literatura 15. Wardle J, Carnell S, Haworth CM, Plomin R. Evidence for a strong
genetic influence on childhood adiposity despite the force of the
obesogenic environment. Am J Clin Nutr. 2008;87(2):398-404.
1. WHO European Regional Obesity Report 2022. Copenhagen: WHO 16. Ouni M, Schürmann A. Epigenetic contribution to obesity. Mamm
Regional Office for Europe; 2022. Licence:CC BY-NC-SA 3.0 IGO. Genome. 2020;31(5-6):134-45.
2. De Lorenzo A, Gratteri S, Gualtieri P, Cammarano A, Bertucci P, Di Renzo 17. Dupont C, Armant DR, Brenner CA. Epigenetics: definition, mechanisms
L. Why primary obesity is a disease? J Transl Med. 2019;17(1):169. and clinical perspective. Semin Reprod Med. 2009;27(5):351-7.
3. Masood B, Moorthy M. Causes of obesity: a review. Clin Med (Lond). 18. Blake-Lamb TL, Locks LM, Perkins ME, Woo Baidal JA, Cheng ER, Taveras
2023;23(4):284-91. EM. Interventions for childhood obesity in the first 1,000 days A
4. Powell-Wiley TM, Poirier P, Burke LE, Després JP, Gordon-Larsen systematic review. Am J Prev Med. 2016; 50(6):780-9.
P, Lavie CJ, et al; American Heart Association Council on Lifestyle 19. Pietrobelli A, Agosti M; MeNu Group. Nutrition in the First 1000 Days:
and Cardiometabolic Health; Council on Cardiovascular and Stroke Ten practices to minimize obesity emerging from published science. Int
Nursing; Council on Clinical Cardiology; Council on Epidemiology and J Environ Res Public Health. 2017;14(12):1491.
Prevention; and Stroke Council. Obesity and Cardiovascular Disease: A
Scientific Statement From the American Heart Association. Circulation. 20. Szczyrska J. Pediatric obesity - time to act as early as possible. Pediatr
2021;143(21):e984-e1010. Endocrinol Diabetes Metab. 2023;29(4):267-73.
5. Trandafir LM, Temneanu OR. Pre and post-natal risk and determination 21. Broussard JL, Klein S. Insufficient sleep and obesity: cause or
of factors for child obesity. J Med Life. 2016;9(4):386-391. consequence. Obesity (Silver Spring). 2022; 30(10):1914-6.
6. Chung ST, Krenek A, Magge SN. Childhood obesity and cardiovascular 22. Pérez-Muñoz C, Carretero-Bravo J, Ortega-Martín E, Ramos-Fiol B,
disease risk. Curr Atheroscler Rep. 2023;25(7):405-15. Ferriz-Mas B, Díaz-Rodríguez M. Interventions in the first 1000 days to
prevent childhood obesity: a systematic review and quantitative content
7. NCD Risk Factor Collaboration (NCD-RisC). Worldwide trends in analysis. BMC Public Health. 2022;22(1):2367.
body-mass index, underweight, overweight, and obesity from 1975
to 2016: a pooled analysis of 2416 population-based measurement 23. Schwarzenberg SJ, Georgieff MK; Committee on Nutrition. Advocacy
studies in 128•9 million children, adolescents, and adults. Lancet. 2017; for improving nutrition in the first 1000 days to support childhood
390(10113):2627-42. development and adult health. Pediatrics. 2018;141(2):e20173716.
8. Ellison-Barnes A, Johnson S, Gudzune K. Trends in obesity prevalence 24. Lee JS, Jin MH, Lee HJ. Global relationship between parent and child
among adults aged 18 through 25 Years, 1976-2018. JAMA. obesity: a systematic review and meta-analysis. Clin Exp Pediatr.
2021;326(20):2073-2074. 2022;65(1):35-46.
9. Simmonds M, Llewellyn A, Owen CG, Woolacott N. Predicting adult 25. Thaker VV. Genetic and epigenetic causes of obesity. Adolesc Med State
obesity from childhood obesity: a systematic review and meta-analysis. Art Rev. 2017 Fall;28(2):379-405.
Obes Rev. 2016;17(2):95-107.
26. Díaz-Rodríguez M, Pérez-Muñoz C, Carretero-Bravo J, Ruíz-Ruíz C,
10. K. Zdravković D, Radlović N. Gojaznost. U: Bogdanović R, Radlović N, Serrano-Santamaría M, Ferriz-Mas BC. Early risk factors for obesity in
urednici. Pedijatrija - udžbenik za poslediplomsko usavršavanje lekara, the first 1000 days-Relationship with body fat and BMI at 2 Years. Int J
2. izdanje. Beograd: Akademska misao; 2022. str. 298-303. Environ Res Public Health. 2021;18(15):8179.
11. Keller M, Svensson SIA, Rohde-Zimmermann K, Kovacs P, Böttcher Y. 27. Pan XF, Tang L, Lee AH, Binns C, Yang CX, Xu ZP, et al. Association
Genetics and epigenetics in obesity: What do we know so far? Curr between fetal macrosomia and risk of obesity in children under 3 years
Obes Rep. 2023;12(4):482-501. in Western China: a cohort study. World J Pediatr. 2019 Apr;15(2):153-60.
12. Andrews P, Johnson RJ. Evolutionary basis for the human diet: 28. Moore BF, Harrall KK, Sauder KA, Glueck DH, Dabelea D. Neonatal
consequences for human health. J Intern Med. 2020; 287(3):226-37. adiposity and childhood obesity. Pediatrics. 2020;146(3):e20200737.
13. Albuquerque D, Stice E, Rodríguez-López R, Manco L, Nóbrega 29. Bammann K, Peplies J, De Henauw S, Hunsberger M, Molnar D, Moreno
C. Current review of genetics of human obesity: from molecular LA; IDEFICS Consortium. Early life course risk factors for childhood
mechanisms to an evolutionary perspective. Mol Genet Genomics. obesity: the IDEFICS case-control study. PLoS One. 2014;9(2):e86914.
2015;290(4):1191-221.
30. Chu S, Zhang Y, Jiang Y, Sun W, Zhu Q, Liu S, et al. Cesarean section and
14. Herrera BM, Keildson S, Lindgren CM. Genetics and epigenetics of risks of overweight and obesity in school-aged children: a population-
obesity. Maturitas. 2011;69(1):41-9. based study. QJM. 2018;111(12):859-65.
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